Synergistic Progression of Nanoparticle Dynamics in Stenosed Arteries

• Sara I. Abdelsalam ^[1] ; M. M. Bhatti ^[2]
  1. [1] British University in Egypt

     British University in Egypt

     Egipto

     
  2. [2] North-West University

     North-West University

     Tlokwe City Council, Sudáfrica

     
• Localización: Qualitative theory of dynamical systems, ISSN 1575-5460, Vol. 24, Nº 1, 2025
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • This article examines the behavior of blood when exposed to gold and copper nanoparticles. The assumption is made that the blood flow is incompressible as a result of the influence of electro-magnetohydrodynamic phenomena. The fluid is undergoing propagation inside an artery that is experiencing stenosis. Additional elements, such as viscous dissipation, heat production or absorption effects, and convection processes, are also considered. The mathematical modeling has been conducted using the energy and momentum equations. The resultant equations are solved analytically using the perturbation technique, and solutions are shown up to third-order approximations.

    The present study presents a discussion on the computational findings pertaining to the velocity profile, wall shear stress, impedance profile, and thermal profile. Furthermore, the use of streamlines has also been employed to examine trapping processes.

    The findings obtained from this study have significant ramifications, which might potentially bring about a transformative shift in the field of biomedical applications and treatments, namely in the realm of cardiovascular medicine. It has been noticed that when heat is introduced, the arterial walls undergo slight expansion. This expansion increases the cross-sectional area of the stenosed region, thereby reducing the constriction and lowering impedance. This study contributes to the advancement of knowledge by examining the behavior of blood in stenosed arteries when hybrid copper–gold nanoparticles are present. By doing so, it creates a basis for the development of novel and focused strategies to tackle cardiovascular diseases specifically in the context of stenosis.

• Referencias bibliográficas
  • 1. Cho, K., Wang, X., Nie, S., Chen, Z.G., Shin, D.M.: Therapeutic nanoparticles for drug delivery in cancer. Clin. Cancer Res. 14(5), 1310–1316...
  • 2. Dreaden, E.C., Alkilany, A.M., Huang, X., Murphy, C.J., El-Sayed, M.A.: The golden age: gold nanoparticles for biomedicine. Chem. Soc....
  • 3. Hwu, J.R., Lin, Y.S., Josephrajan, T., Hsu, M.H., Cheng, F.Y., Yeh, C.S.: Targeted paclitaxel by conjugation to iron oxide and gold nanoparticles....
  • 4. Benjamin, E.J., Muntner, P., Alonso, A., Bittencourt, M.S., Callaway, C.W., Carson, A.P., Chamberlain, A.M., Chang, A.R., Cheng, S., Das,...
  • 5. Manchi, R., Ponalagusamy, R.: Modeling of pulsatile EMHD flow of Au-blood in an inclined porous tapered atherosclerotic vessel under periodic...
  • 6. Padma, R., Tamil Selvi, R., Ponalagusamy, R.: Effects of slip and magnetic field on the pulsatile flow of a Jeffrey fluid with magnetic...
  • 7. Manchi, R., Ponalagusamy, R.: Pulsatile flow of EMHD micropolar hybrid nanofluid in a porous bifurcated artery with an overlapping stenosis...
  • 8. Abdelsalam, S.I., Alsharif, A.M., Abd Elmaboud, Y., Abdellateef, A.I.: Assorted kerosene-based nanofluid across dual-zone vertical annulus...
  • 9. Abdelsalam, S.I., Bhatti, M.M.: Unraveling the nature of nano-diamonds and silica in a catheterized tapered artery: highlights into hydrophilic...
  • 10. Abdelsalam, S. I., Mekheimer, Kh., Zaher, A. Z: Dynamism of a hybrid Casson nanofluid with laser radiation and chemical reaction through...
  • 11. Bhatti, M. M., Abdelsalam, S. I: Bio-inspired peristaltic propulsion of hybrid nanofluid flow with Tantalum (Ta) and Gold (Au) nanoparticles...
  • 12. Lee, Y.E.K., Kopacz, A.M., Kirkwood, J.E., Gregorio, A., Kowalczyk, B., Agarwal, A., Stavis, C., Somasundaran, P., Osuji, C.O.: Shape-dependent...
  • 13. Debbage, P.: Targeted drugs and nanomedicine: present and future. Curr. Pharm. Des. 16(22), 2473–2480 (2010)
  • 14. Daraee, H., Eatemadi, A., Abbasi, E., Fekri Aval, S., Kouhi, M., Akbarzadeh, A.: Application of gold nanoparticles in biomedical and drug...
  • 15. Huang, X., Jain, P.K., El-Sayed, I.H., El-Sayed, M.A.: Gold nanoparticles: interesting optical properties and recent applications in cancer...
  • 16. Chen, H., Dorrigan, A., Saad, S., Hare, D.J., Cortie, M.B., Valenzuela, S.M.: In vivo study of spherical gold nanoparticles: inflammatory...
  • 17. Rai, M., Deshmukh, S.D., Ingle, A.P., Gade, A.K.: Silver nanoparticles: the powerful nanoweapon against multidrug-resistant bacteria....
  • 18. Jones, S.W., Roberts, R.A., Robbins, G.R., Perry, J.L., Kai, M.P., Chen, K., Bo, T., Napier, M.E., Ting, J.P., DeSimone, J.M., Bear, J.E.:...
  • 19. El-Zahar, E., Rashad, A., Saad, W., Seddek, L.: Magneto-hybrid nanofluids flow via mixed convection past a radiative circular cylinder....
  • 20. Jakeer, S., Reddy, P.B., Rashad, A., Nabwey, H.A.: Impact of heated obstacle position on magnetohybrid nanofluid flow in a lid-driven...
  • 21. Bhatti, M., Abdelsalam, S.I.: Scientific breakdown of a ferromagnetic nanofluid in hemodynamics: enhanced therapeutic approach. Math Model....
  • 22. Soltanian, F., Dehghan, M., Karbassi, S.M.: Solution of the differential algebraic equations via homotopy perturbation method and their...
  • 23. Bhatti, M.M., Bég, O.A., Ellahi, R., Abbas, T.: Natural convection non-newtonian emhd dissipative flow through a microchannel containing...
  • 24. Alim, M.A., Kawser, M.A.: Illustration of the homotopy perturbation method to the modified nonlinear single degree of freedom system....
  • 25. Umadevi, C., Dhange, M., Haritha, B., Sudha, T.: Flow of blood mixed with copper nanoparticles in an inclined overlapping stenosed artery...
  • 26. Ardahaie, S.S., Amiri, A.J., Amouei, A., Hosseinzadeh, K., Ganji, D.D.: Investigating the effect of adding nanoparticles to the blood...
  • 27. Seikh, A.H., Akinshilo, A.T., Taheri, M.H., Rahimi-Gorji, M., Alharthi, N., Khan, I., Khan, A.R.: Influence of the nanoparticles and uniform...
  • 28. Vu, M.N., Kelly, H.G., Wheatley, A.K., Peng, S., Pilkington, E.H., Veldhuis, N.A., Davis, T.P., Kent, S.J., Truong, N.P.: Cellular interactions...
  • 29. Akbar, N.S.: Blood flow analysis of Prandtl fluid model in tapered stenosed arteries. Ain. Shams. Eng. J. 5(4), 1267–1275 (2014)