Decision making in kidney paired donation programs with altruistic donors

• Autores: Yijiang Li, Peter X.-K. Song, Alan B. Leichtman, Michael A. Rees, John D. Kalbfleisch
• Localización: Sort: Statistics and Operations Research Transactions, ISSN 1696-2281, Vol. 38, Nº. 1, 2014, págs. 53-72
• Idioma: inglés
• Enlaces
  • Texto completo (pdf)
• Dialnet Métricas: 1 Cita
• Resumen

  • In recent years, kidney paired donation has been extended to include living non-directed or altruistic donors, in which an altruistic donor donates to the candidate of an incompatible donor candidate pair with the understanding that the donor in that pair will further donate to the candidate of a second pair, and so on; such a process continues and thus forms an altruistic donor-initiated chain. In this paper, we propose a novel strategy to sequentially allocate the altruistic donor (or bridge donor) so as to maximize the expected utility; analogous to the way a computer plays chess, the idea is to evaluate different allocations for each altruistic donor (or bridge donor) by looking several moves ahead in a derived look-ahead search tree. Simulation studies are provided to illustrate and evaluate our proposed method.

• Referencias bibliográficas
  • Abraham, D. J., Blum, A. and Sandholm, T. (2007). Clearing algorithms for barter exchange markets: Enabling nationwide kidney exchanges. Ec’07:...
  • Ashlagi, I., Gilchrist, D. S., Roth, A. E. and Rees, M. A. (2011). Nonsimultaneous chains and dominos in kidney-paired donation-revisited....
  • Evans, R. W., Manninen, D. L., Garrison, L. P., Hart, L. G., Blagg, C. R., Gutman, R. A., Hull, A. R. and
  • Lowrie, E. G. (1985). The quality of life of patients with end-stage renal disease. New England Journal of Medicine, 312(9): 553–559.
  • Gentry, S. E., Montgomery, R. A., Swihart, B. J. and Segev, D. L. (2009). The roles of dominos and nonsimultaneous chains in kidney paired...
  • Li, Y. (2012). Optimization and simulation of kidney paired donation programs (doctoral dissertation). University of Michigan, Ann Arbor.
  • Li, Y., Kalbfleisch, J. D., Song, P. X.-K., Zhou, Y., Leichtman, A. B. and Rees, M. A. (2013). Optimal decisions for organ exchanges in a...
  • Maiers, M., Gragert, L. and Klitz, W. (2007). High-resolution hla alleles and haplotypes in the united states population. Human Immunology,...
  • Montgomery, R. A., Gentry, S. E., Marks, W. H., Warren, D. S., Hiller, J., Houp, J., Zachary, A. A., Melancon, J. K., Maley, W. R., Rabb,...
  • Rapaport, F. T. (1986). The case for a living emotionally related international kidney donor exchange registry. Transplantation Proceedings,...
  • Rees, M. A., Kopke, J. E., Pelletier, R. P., Segev, D. L., Rutter, M. E., Fabrega, A. J., Rogers, J., Pankewycz, O. G., Hiller, J., Roth,...
  • Roth, A. E., Sönmez, T. and Ünver, M. U. (2004). Kidney exchange. Quarterly Journal of Economics, 119(2): 457–488.
  • Roth, A. E., Sönmez, T. and Ünver, M. U. (2007). Efficient kidney exchange: Coincidence of wants in markets with compatibility-based preferences....
  • Roth, A. E., Sönmez, T., Ünver, M. U., Delmonico, F. L. and Saidman, S. L. (2006). Utilizing list exchange and nondirected donation through...
  • Russell, J. D., Beecroft, M. L., Ludwin, D. and Churchill, D. N. (1992). The quality of life in renal transplantation-a prospective study....
  • Schaubel, D. E., Wolfe, R. A., Sima, C. S. and Merion, R. M. (2009). Estimating the effect of a timedependent treatment by levels of an internal...
  • Segev, D. L., Kucirka, L. M., Gentry, S. E. and Montgomery, R. A. (2008). Utilization and outcomes of kidney paired donation in the united...
  • Wolfe, R. A., Ashby, V. B., Milford, E. L., Ojo, A. O., Ettenger, R. E., Agodoa, L. Y. C., Held, P. J. and Port, F. K. (1999). Comparison...
  • Wolfe, R. A., McCullough, K. P., Schaubel, D. E., Kalbfleisch, J. D., Murray, S., Stegall, M. D. and Leichtman, A. B. (2008). Calculating...