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Killer Cell Dynamics

Imagen de portada del libro Killer Cell Dynamics

Información General

  • Autores: Dominik Wodarz
  • Editores: New York : Springer, 2007
  • Año de publicación: 2007
  • País: Estados Unidos
  • Idioma: inglés
  • ISBN: 978-0-387-30893-7, 978-0-387-68733-9
  • Texto completo no disponible (Saber más ...)

Resumen

  • This book reviews how mathematical and computational approaches can be useful to help us understand how killer T-cell responses work to fight viral infections. It also demonstrates, in a writing style that exemplifies the point, that such mathematical and computational approaches are most valuable when coupled with experimental work through interdisciplinary collaborations. Designed to be useful to immunoligists and viroligists without extensive computational background, the book covers a broad variety of topics, including both basic immunological questions and the application of these insights to the understanding and treatment of pathogenic human diseases.

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Índice

  • Viruses and Immune Responses: A Dynamical View.- Models of CTL Responses and Correlates of Virus Control.- CTL Memory.- CD4 T Cell Help.- Immunodominance.- Multiple Infections and CTL Dynamics.- Control Versus CTL-Induced Pathology.- Lytic Versus Nonlytic Activity.- Dynamical Interactions Between CTL and Antibody Responses.- Effector Molecules and CTL Homeostasis.- Virus-Induced Subversion of CTL Responses.- Boosting Immunity Against Immunosuppressive Infections.- Evolutionary Aspects of Immunity.- References.- Index.



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