Resumen de Genome-Wide Association Studies:: a distance-based approach

Itziar Irigoien Garbizu , Bru Cormand Rifa, María Soler Artigas, Cristina Sánchez Mora, Josep Antoni Ramos-Quiroga , Concepción Arenas Solá

• With the increase in the production of genome-wide association studies (GWAS), the analysis of such data sets with thousands of potential predictive single nucleotide-polymorphisms (SNPs) has become crucial in biomedical research. Here we propose a new method to identify SNPs related with a disease in case-control studies. The method provides two ordered lists of SNPs (with causal or protective alleles) that provide a useful tool to help the researcher to decide where to focus attention in a first stage.