Review of Recent Methodological Developments in Group-Randomized Trials: Part 2--Analysis.

Autores: Elizabeth L. Turner, Melanie Prague, John A. Gallis, Fan Li, David M Murray
Localización: American journal of public health, ISSN 0090-0036, Vol. 107, Nº. 7, 2017, págs. 1078-1086
Idioma: inglés
DOI: 10.2105/ajph.2017.303707
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Resumen
- In 2004, Murray et al. reviewed methodological developments in the design and analysis of group-randomized trials (GRTs). We have updated that review with developments in analysis of the past 13 years, with a companion article to focus on developments in design. We discuss developments in the topics of the earlier review (e.g., methods for parallel-arm GRTs, individually randomized group-treatment trials, and missing data) and in new topics, including methods to account for multiple-level clustering and alternative estimation methods (e.g., augmented generalized estimating equations, targeted maximum likelihood, and quadratic inference functions). In addition, we describe developments in analysis of alternative group designs (including stepped-wedge GRTs, networkrandomized trials, and pseudocluster randomized trials), which require clustering to be accounted for in their design and analysis. [ABSTRACT FROM AUTHOR]