The aim of this first work is the resolution of an abstract complete second order differential equation of elliptic type with variable operator coefficients set in a small length interval. We obtain existence, uniqueness and maximal regularity results under some appropriate differentiability assumptions combining those of Yagi (1977) and Da Prato-Grisvard (1975). An example for the Laplacian in a regular domain of will illustrate the theory. A forthcoming work (Part II) will complete the present one by the study of the Steklov-Poincaré operator related to this equation when the length of the interval tends to zero.
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