Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

• Autores: Xavier Bardina i Simorra , Laura Fernández Ruano, Elisabet Piñeiro, Jordi Surrallés Calonge , Antonia Velázquez
• Localización: Sort: Statistics and Operations Research Transactions, ISSN 1696-2281, Vol. 30, Nº. 2, 2006, págs. 193-204
• Idioma: inglés
• Títulos paralelos:
  • Modelos estadísticos para estudiar concentraciones subtóxicas para algunos mutágenos estándar en tres líneas celulares de cáncer de colon.
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• Resumen

  • The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.