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Recent advances in copula-based methods for dependent censoring

  • Gilles Crommen [1] ; Negera Wakgari Deresa [1] ; Myrthe D'Haen [1] ; Jie Ding [1] ; Ilias Willems [1] ; Ingrid Van Keilegom [1] Árbol académico
    1. [1] KU Leuven

      KU Leuven

      Arrondissement Leuven, Bélgica

  • Localización: Sort: Statistics and Operations Research Transactions, ISSN 1696-2281, Vol. 49, Nº. 1, 2025, págs. 3-41
  • Idioma: inglés
  • DOI: 10.57645/20.8080.02.21
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  • Resumen
    • When modeling time-to-event data that are subject to right censoring, it is commonly as- sumed that the survival time T and the censoring time C are independent. However, this assumption frequently fails in practice, leading to biased estimators and testing proce- dures having invalid type 1 error rates. To overcome this issue, several models relaxing the independent censoring assumption have been proposed in the literature. Among these, copula-based approaches have become popular due to their ability to separately model the marginal distributions of T and C and their dependence structure. This review paper gives a comprehensive overview of recent advances in copula-based methods for dependent censoring, along with a discussion of the most important historical papers on this topic. As it is well known that the distribution of (T,C) (and hence of T ) is not identifed in a fully nonparametric way, we examine different strategies to achieve model identifability. These strategies consist of imposing assumptions on either the copula or the marginal distributions of T and C. Both of these approaches will be discussed, with and without covariates. We also consider the case where a dependent censoring time is accompanied by an additional latent independent censoring time. Lastly, we briefy explain alternative approaches that are not based on copulas.


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