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Intensity modulated radiation therapy treatment plan optimization

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Abstract

In this paper, we provide an overview of the state-of-the-art of optimization models for static radiation therapy treatment planning, focusing in particular on intensity modulated radiation therapy (IMRT) by (i) establishing a novel connection between risk management and radiation therapy treatment planning, and (ii) unifying and contrasting two different modeling approaches. In addition, we discussion recent and ongoing technological developments which show that this area of research is a lively and promising one that can continue to help patients by improving the clinical practice of radiation therapy.

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Authors and Affiliations

  1. Department of Industrial and Operations Engineering, The University of Michigan, 1205 Beal Avenue, Ann Arbor, MI, 48109-2117, USA

    H. Edwin Romeijn

  2. View Ray Inc., Chagrin Highlands Center, 2000 Auburn Drive, Suite 200, Cleveland, OH, 44122, USA

    James F. Dempsey

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  1. H. Edwin Romeijn
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Correspondence to H. Edwin Romeijn.

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This invited paper is discussed in the comments available at: http://dx.doi.org/10.1007/s11750-008-0065-0, http://dx.doi.org/10.1007/s11750-008-0066-z, http://dx.doi.org/10.1007/s11750-008-0067-y, http://dx.doi.org/10.1007/s11750-008-0068-x, http://dx.doi.org/10.1007/s11750-008-0069-9.

This work was supported by the National Science Foundation under grant no. DMI-0457394/CMMI-0852727.

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Romeijn, H.E., Dempsey, J.F. Intensity modulated radiation therapy treatment plan optimization. TOP 16, 215–243 (2008). https://doi.org/10.1007/s11750-008-0064-1

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